Hoppe lab

Understanding the principles of protein homeostasis in cancer and aging

The maintenance of protein homeostasis, or proteostasis, involves folding and degradation of damaged proteins. It is commonly thought that age-related impairment of protein quality control (PQC) affects general proteostasis networks, causing enhanced aggregation of misfolded proteins that can be toxic for cells and shortens organismal lifespan.

Univ.-Prof. Dr. rer. nat. Thorsten Hoppe

CECAD Cologne and Institute for Genetics
Tel.  +49 221 478 84218